Ruda Prestes e Albuquerque in research grants and scholarships supported by FAPESP.
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Aldehydes are highly reactive molecules in biological systems, where they bind to biomolecules such as DNA and proteins, resulting in functional jeopardy. Aldehydic attack may have an exogenous source, when directly absorbed from the environment, or be generated endogenously, after ethanol metabolism (generating acetaldehyde) or during mitochondrial lipid peroxidation (forming 4-hydroxyno…
Ischemic diseases represent the first cause of mortality and morbidity worldwide. The process known as Ischemia-Reperfusion (I/R) causes irreparable damage at the afflicted organs (i.e. heart, brain and kidney) as a result of the great variation of the tissue's oxygen tension. The reperfusion of ischemic tissue (low oxygen tension) results in an abrupt oxygen income (high oxygen tension),…
Aldehydes are known as a class of highly reactive molecules and one of the most important drivers of redox damage in living cells. Aldehyde levels are mainly controlled by enzymes from Aldehyde Dehydrogenase superfamily (ALDH), of which ALDH2 is the most well characterized member. The main acetaldehyde metabolizing enzyme is mainly known by a mutation (E540K, named ALDH2*2) present in abo…
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 3 / 3 | All Scholarships |
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