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Paulo Roberto das Dores da Silva

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Universidade de São Paulo (USP). Instituto de Química de São Carlos (IQSC)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

PhD in Sciences from the Institute of Chemistry of São Carlos, University of São Paulo (2015). Between 2006 and 2010 Dr. Dores-Silva acquired extensive experience in the field of analytical chemistry during the scientific initiation, highlighting the purification and structural characterization of macro-biomolecules in soil and organic fertilizers. He obtained mastery of techniques such as: ultraviolet in the UV-Vis region, infrared, fluorescence and pyrolysis coupled to mass spectrometry. During his PhD at the University of São Paulo in the area of Biochemistry with emphasis on the production and purification of recombinant proteins, as well as biophysical techniques of structural and functional characterization, among them: circular dichroism (CD) fluorescence, analytical molecular exclusion chromatography, analytical ultracentrifugation (AUC), low-angle X-ray scattering (SAXS) differential scanning calorimetry (DSC) and isothermal titration calorimetry (ITC). He currently develops postdoctoral studies aiming at obtaining structural and functional data of molecular chaperones of the Hsp70 family, membranes and beta amyloid oligomerization. (Source: Lattes Curriculum)

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Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (6)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications6
Citations8
Cit./Article1.3
Data from Web of Science

BATISTA, FERNANDA A. H.; DORES-SILVA, PAULO R.; BORGES, JULIO C.. Molecular Chaperones Involved in Protein Recovery from Aggregates are Present in Protozoa Causative of Malaria and Leishmaniasis. CURRENT PROTEOMICS, v. 16, n. 1, p. 12-21, . Web of Science Citations: 0. (14/07206-6, 14/16646-0, 12/50161-8, 11/23110-0)

DORES-SILVA, P. R.; BELOTI, L. L.; MINARI, K.; SILVA, S. M. O.; BARBOSA, L. R. S.; BORGES, J. C.. Structural and functional studies of Hsp70-escort protein-Hep1-of Leishmania braziliensis. International Journal of Biological Macromolecules, v. 79, p. 903-912, . Web of Science Citations: 4. (14/07206-6, 11/23110-0, 14/16646-0)

DORES-SILVA, PAULO ROBERTO; CAUVI, DAVID M.; KIRALY, VANESSA T. R.; BORGES, JULIO C.; DE MAIO, ANTONIO. Human HSPA9 (mtHsp70, mortalin) interacts with lipid bilayers containing cardiolipin, a major component of the inner mitochondrial membrane. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, v. 1862, n. 11, . Web of Science Citations: 0. (16/22477-1, 17/07335-9, 14/16646-0, 12/50161-8)

KIRALY, VANESSA T. R.; DORES-SILVA, PAULO R.; SERRAO, VITOR H. B.; CAUVI, DAVID M.; DE MAIO, ANTONIO; BORGES, JULIO C.. Thermal aggregates of human mortalin and Hsp70-1A behave as supramolecular assemblies. International Journal of Biological Macromolecules, v. 146, p. 320-331, . Web of Science Citations: 0. (17/26131-5, 14/07206-6, 11/23110-0, 12/50161-8, 17/07335-9, 14/16646-0)

DORES-SILVA, PAULO R.; NISHIMURA, LETICIA S.; KIRALY, VANESSA T. R.; BORGES, JULIO C.. Structural and functional studies of the Leishmania braziliensis mitochondrial Hsp70: Similarities and dissimilarities to human orthologues. Archives of Biochemistry and Biophysics, v. 613, p. 43-52, . Web of Science Citations: 2. (12/50161-8, 14/16646-0, 14/07206-6, 11/23110-0)

DORES-SILVA, PAULO ROBERTO; CAUVI, DAVID M.; COTO, AMANDA L. S.; KIRALY, VANESSA T. R.; BORGES, JULIO C.; DE MAIO, ANTONIO. Interaction of HSPA5 (Grp78, BIP) with negatively charged phospholipid membranes via oligomerization involving the N-terminal end domain. CELL STRESS & CHAPERONES, v. 25, n. 6, . Web of Science Citations: 2. (12/50161-8, 14/16646-0, 17/26131-5, 16/22477-1, 17/07335-9)

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