Davi Jardim Martins
CV Lattes
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Biologist graduated at the University of São Paulo in 2016. Realized projects in Professor Dr. Carlos Frederico Martins Menck´s DNA Repair laboratory, in University of São Paulo. Worked for two months in Professor Dr. Catherine Green´s Chromossome Dinamics laboratory, at Oxford University. Concluded technical course in chemistry at the Technical School Getúlio Vargas. Has experience in Chemistry, developed research project with emphasis in Environmental Chemistry, the Institute of Energy and Nuclear Research (IPEN). (Source: Lattes Curriculum)
- Mechanisms of translesion synthesis in human cells, BP.DD
Abstract
Ultraviolet (UV) light is a highly carcinogenic agent to which the human is exposed, that damages the cellular components and deforms the DNA strand and can result in cell death or gene instability. The lesions formed by UV light are usually removed by the Nucleotide Excision Repair mechanism (NER). When these lesions remain until the replication, there is a process known as translesion...
- Replication of ultraviolet-damaged DNA in human cells: different mechanisms for different lesions?, BP.IC
Abstract
Ultraviolet light (UV) is a highly carcinogenic agent to which all living beings are exposed. When absorbed by the DNA molecule, UV-light induces mainly lesions of two types: cyclobutane pyrimidine dimers (CPD) and pyrimidine 6-4 pyrimidone (6-4PP). These lesions distort the double helix, promoting a block to the replication and transcription of DNA, what may result in genomic instabili...
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