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Samanta Etel Treiger Borborema de Carvalho

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Secretaria da Saúde (São Paulo - Estado). Coordenadoria de Controle de Doenças (CCD). Instituto Adolfo Lutz (IAL)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

I am a bachelor in Biological Sciences, University of Mogi das Cruzes (2002). Specialist in Protozoology in Public Health, Hospital das Clínicas, Faculty of Medicine, University of São Paulo (2004). Master (2005) and PhD (2010) in Biological Applications of Nuclear Technology, IPEN/USP. Doctorate Sandwich at the University of Zurich, Switzerland (2009). Postdoctoral by the Coordinator of Disease Control of the State Department of Health/SP. Between 2009 and 2012, I was an Assistant Researcher at the Adolfo Lutz Institute. Currently, I am a Research Scientist V at the Adolfo Lutz Institute. I am the vice-director of the Department for Systemic Parasitoses at IAL. I work with drug development for the treatment of neglected parasitic diseases. I have experience in human parasitic protozoology, molecular biology and pharmacology, with emphasis on drug delivery system and pharmacokinetic. I work mainly on the following topics: preclinical evaluation of natural and synthetic compounds and traditional drugs against protozoa causing Leishmaniasis and Chagas disease. I work with in vitro assays for drug screening, determination of its efficacy, cytotoxicity and mechanism of action; In vivo assays to determine the effective dose, route of administration and pharmacokinetic profile; Use of the drug delivery system to improve drug efficacy, and molecular biology (gene expression, qPCR and sequencing) for parasite identification and quantification. At the moment, I am coordinating a CNPq project in drug discovery for visceral leishmaniasis. I have collaborative national and international projects with Unifesp and UFABC (Brazil), Universität Munster (Germany) and University of Auckland (New Zealand). (Source: Lattes Curriculum)

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Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (2)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Data from Web of Science

TREIGER BORBOREMA, SAMANTA ETEL; OSSO JUNIOR, JOAO ALBERTO; TEMPONE, ANDRE GUSTAVO; DE ANDRADE JUNIOR, HEITOR FRANCO; DO NASCIMENTO, NANCI. Pharmacokinetic of meglumine antimoniate encapsulated in phosphatidylserine-liposomes in mice model: A candidate formulation for visceral leishmaniasis. BIOMEDICINE & PHARMACOTHERAPY, v. 103, p. 1609-1616, . Web of Science Citations: 2.

MENDES, VIVIANE DE MELO; TEMPONE, ANDRE GUSTAVO; TREIGER BORBOREMA, SAMANTA ETEL. Antileishmanial activity of Hi-antihistamine drugs and cellular alterations in Leishmania (L.) infantum. Acta Tropica, v. 195, p. 6-14, . Web of Science Citations: 0.

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