Abstract
Oropouche virus (OROV) belongs to the family Bunyaviridae, genus Orthobunyavirus, serogroup Simbu, and is the second most frequent cause of arboviral illness in Brazil, surpassed only by dengue. OROV is transmitted by the bite of the vector Culicoides paraensis and causes acute febrile disease in humans, with significant public health impact, mainly in the Amazon. OROV genome is composed …