Jéssica Silva dos Santos in research grants and scholarships supported by FAPESP.
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Glioblastoma multiforme (GBM) represents a significant portion of neurological tumors. It is characterized by poorly differentiated neoplastic astrocytes with areas of vascular proliferation and necrosis. The survival rate of the patients is inversely proportional to the degree of the tumor, where grade IV is the most aggressive with a relatively short prognosis. Biological heterogeneity …
Mutations and single nucleotide polymorphisms (SNPs) in DNA repair genes have been described in colorectal cancer (CRC). One of the mainly DNA repair pathways is homologous recombination (HR). When HR is altered by gene mutation, cells are not able to perform DNA repair, resulting in apoptosis or tumorigenesis. The lysine methylation of histone proteins affects many aspects of the chromos…
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