Ernesto da Silveira Goulart Guimarães
CV Lattes
Universidade de São Paulo (USP). Instituto de Biociências (IB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Ph.D. in Genetics at the University of Sao Paulo in 2019. Graduated in Pharmacy at the Federal University of Juiz de Fora in 2014. He was a fellow at the Department of Bioengineering at Temple University, Philadelphia, at the TIME Research Center, Temple Institute for Regenerative Medicine and Engineering under the advisorship of Dr. Peter I. Lelkes. He holds a Masters in Biological Sciences: Genetics and Biotechnology from the Federal University of Juiz de Fora. and a PhD in Biological Sciences: Genetics, under the guidance of Dr. Mayana Zatz. Has experience and works in the field of Physiology, Cell Biology and Genetics. He is currently a fellow at the Center for Human Genome and Stem Cell Research - USP and works in the area of ​​tissue bioengineering/biomaterials, with a focus on hepatic tissue engineering and genetic engineering, focusing on xenotransplantation. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| Researchers create functional mini-liver by 3D bioprinting |
| Brazil will have the technology to transplant pig organs into humans |
- Development of universal hepatic organoids produced from IPS cells, BP.PD
Abstract
Hepatic organoid technology holds great promise for the development of future Regenerative Medicine strategies to treat patients with severe liver disease. Recently, some studies have demonstrated robust protocols for isogenic organoid generation using induced Pluripotent Stem cells (iPS). However, using patient's specific iPS-derived cells poses a major challenge for a translational pe...
- Development of functional hepatic by-pass using iPSCs derived cells, BP.DR
Abstract
The liver is a key organ in the regulation of metabolism and hemodynamics. Several acute and chronic liver diseases (i.e. resulting from toxic exposures or congenital diseases) progress for a severe loss of hepatic function. Currently, the only therapeutic option for patients with end-stage and/or progressively severe liver disease is the partial or total organ transplant. Due to the sh...
| 1 / 1 | Ongoing scholarships in Brazil |
| 1 / 1 | Completed scholarships in Brazil |
| 2 / 2 | All Scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 3 |
| Citations | 9 |
| Cit./Article | 3.0 |
| Data from Web of Science | |
ARAUJO, BRUNO H. S.; KAID, CAROLINI; DE SOUZA, JANAINA S.; DA SILVA, SERGIO GOMES; GOULART, ERNESTO; CAIRES, LUIZ C. J.; MUSSO, CAMILA M.; TORRES, LAILA B.; FERRASA, ADRIANO; HERAI, ROBERTO; et al. Down Syndrome iPSC-Derived Astrocytes Impair Neuronal Synaptogenesis and the mTOR Pathway In Vitro. Molecular Neurobiology, v. 55, n. 7, p. 5962-5975, JUL 2018. Web of Science Citations: 3.
RIVAS, MARIA PRATES; MARQUES AGUIAR, TALITA FERREIRA; FERNANDES, GUSTAVO RIBEIRO; CAIRES, LUIZ CARLOS; GOULART, ERNESTO; TELLES-SILVA, KAYQUE ALVES; CYPRIANO, MONICA; CAMINADA DE TOLEDO, SILVIA REGINA; ROSENBERG, CARLA; CARRARO, DIRCE MARIA; et al. TET Upregulation Leads to 5-Hydroxymethylation Enrichment in Hepatoblastoma. FRONTIERS IN GENETICS, v. 10, JUN 12 2019. Web of Science Citations: 0.
KAID, CAROLINI; GOULART, ERNESTO; CAIRES-JUNIOR, LUIZ C.; ARAUJO, BRUNO H. S.; SOARES-SCHANOSKI, ALESSANDRA; BUENO, HELOISA M. S.; TELLES-SILVA, KAYQUE A.; ASTRAY, RENATO M.; ASSONI, AMANDA F.; JUNIOR, ANTONIO F. R.; et al. Zika Virus Selectively Kills Aggressive Human Embryonal CNS Tumor Cells In Vitro and In Vivo. Cancer Research, v. 78, n. 12, p. 3363-3374, JUN 15 2018. Web of Science Citations: 6.