Currently is a Postdoctoral Research Fellow at Harvard University (Boston, USA). Was a Postdoctoral Fellow at São Paulo State University (Araraquara, SP, Brazil; 2019-2022) and at University of Pittsburgh (Pittsburgh, USA; 2018-2019). Received his Ph.D. in Physiology from University of São Paulo (Ribeirão Preto, SP, Brazil; 2013-2018). During his Ph.D., received a fellowship to spend one year at University of Bristol (Bristol, UK; 2016-2017). Received a Specialization in Gerontology from the Multidisciplinary Health Residency Program at Federal University of Triângulo Mineiro (Uberaba, MG, Brazil; 2011-2013) and a Bachelors degree in Physical Education from University of Uberaba (Uberaba, MG, Brazil; 2006-2009). Has experience in Neuroscience and Physiology, with focus on Autonomic Nervous System and on Cardiovascular and Respiratory Physiology. Studies the neural mechanisms and circuits involved in cardiorespiratory control under physiological and pathological conditions. Furthermore, investigates how the nervous system and the immune system can interact in a bidirectional way. Main research techniques: in vivo electrophysiology, manipulation of specific neuronal populations, differentiation of human induced pluripotent stem cells (hIPSC) into neurons, RNA sequencing (RNA-Seq), immunohistochemistry, and fluorescent in situ hybridization (RNAscope) . (Source: Lattes Curriculum)
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Recent evidence has demonstrated that Renovascular Hypertension is characterized not only by an increase in sympathetic activity and activation of the renin-angiotensin-aldosterone system, but also by a peripheral inflammation with increased levels of circulating pro-inflammatory cytokines. Although the conventional therapeutic approaches for hypertension have targeted a reduction of symp…
The role of the carotid body in the context of cardiovascular diseases has been widely explored. In a recently published study (Hypertension 66: 598-603, 2015) our laboratory demonstrated that carotid body attenuate the hypotensive response to electrical stimulation of the carotid sinus/carotid sinus nerve in conscious rats. Although a recent clinical study has been suggested that electri…
The nervous and immune systems interact in a bidirectional manner, but the precise mechanisms governing this interplay are still unclear. Recently, we identified a previously unrecognized mechanism of neuroimmune interaction in which peripheral sensory organs (i.e., the carotid bodies) can detect the pro-inflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) in the blood, activatin…
Although the causes of hypertension-related sympathoexcitation remain unknown, studies conducted in the laboratory of Professor Julian F. R. Paton (University of Bristol, Bristol, UK) have strongly suggested that the carotid body chemoreceptors may be responsible, at least in part, for this exacerbated sympathetic activity. In this way, the carotid body chemoreceptors may contribute both …
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