- Research Grants
Daniela de Vita in research grants and scholarships supported by FAPESP.
Cruzain, the main Trypanosoma cruzi cysteine protease, is an enzyme essential for the life cycle of the parasite and has been used as a viable target to search for enzyme inhibitor drug candidates. The K777 peptidemimetic compound inhibits cruzain in nanomolar concentrations and acts through a mechanism of irreversible inhibition. Analogs or derivatives of the K777 usually contain elect...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)