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Eduardo Maffud Cilli

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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Instituto de Química (IQ)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

I am currently an associate professor at the Institute of Chemistry of Araraquara-UNESP. I hold a Bachelor's Degree in Chemistry from Universidade Estadual Paulista Júlio de Mesquita Filho (1989), a Master's degree in Biological Sciences (Molecular Biology) from the Federal University of São Paulo (1993) and a PhD in Biological Sciences (Molecular Biology) from the Federal University of São Paulo (1997). I am ssociate professor at Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP). My group has experience in Biochemistry, with emphasis on peptides, solid support, solid phase synthesis, fluorescence, EPR, NMR; and antibacterial, antiviral, antifungal and anticancer activity. (Source: Lattes Curriculum)

News published in Agência FAPESP Newsletter about the researcher
Scientists synthesize molecule capable of eliminating hepatitis C virus 
Brazilian and British scientists develop technology to detect several diseases 
Articles published in other media outlets (15 total):
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A Cidade On (São Carlos, SP): Pesquisadores de Araraquara estudam proteína para combater o coronavírus (22/Jul/2020)
Central das Notícias: Pesquisadores de Araraquara estudam proteína para combater o coronavírus (22/Jul/2020)
Biblioteca FMUSP: Ação de 50 compostos sintéticos será testada contra o novo coronavírus (20/Jul/2020)
Beto Ribeiro Repórter: Fapesp: Ação de 50 compostos sintéticos será testada contra o novo coronavírus (20/Jul/2020)
Duna Press : Fapesp: Ação de 50 compostos sintéticos será testada contra o novo coronavírus (20/Jul/2020)
Diário do Rio Claro: Ação de 50 compostos sintéticos será testada contra o novo coronavírus (19/Jul/2020)
Jornal Cidade - Rio Claro: Ação de 50 compostos sintéticos será testada (19/Jul/2020)
Região Noroeste : Ação de 50 compostos sintéticos será testada contra o Covid (18/Jul/2020)
Portal do Governo do Estado de São Paulo: Fapesp: Ação de 50 compostos sintéticos será testada contra o novo coronavírus (17/Jul/2020)
São Carlos em Rede: Ação de 50 compostos sintéticos será testada contra o novo coronavírus (17/Jul/2020)
Folha Nobre: Fapesp: Ação de 50 compostos sintéticos será testada contra o novo coronavírus (17/Jul/2020)
Notícias de Campinas: Fapesp: Ação de 50 compostos sintéticos será testada contra o novo coronavírus (17/Jul/2020)
Atemporal: Ação de 50 compostos sintéticos será testada contra o novo coronavírus (17/Jul/2020)
Mix Vale: Fapesp: Ação de 50 compostos sintéticos será testada contra o novo coronavírus (17/Jul/2020)
O Verídico: Fapesp: Ação de 50 compostos sintéticos será testada contra o novo coronavírus (17/Jul/2020)
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Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (34)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications31
Citations143
Cit./Article4.6
Data from Web of Science

PINTO, MERI EMILI F.; CHAN, LAI YUE; KOEHBACH, JOHANNES; DEVI, SEEMA; GRUNDEMANN, CARSTEN; GRUBER, CHRISTIAN W.; GOMES, MARIO; BOLZANI, VANDERLAN S.; CILLI, EDUARDO MAFFUD; CRAIK, DAVID J.. Cyclotides from Brazilian Palicourea sessilis and Their Effects on Human Lymphocytes. Journal of Natural Products, v. 84, n. 1, p. 81-90, . Web of Science Citations: 0. (19/04381-5, 13/07600-3, 17/17098-4)

SANTOS-FILHO, NORIVAL A.; FERNANDES, RAFAELA S.; SGARDIOLI, BRUNA F.; RAMOS, MATHEUS A. S.; PICCOLI, JULIA P.; CAMARGO, ILANA L. B. C.; BAUAB, TAIS M.; CILLI, EDUARDO M.. Antibacterial Activity of the Non-Cytotoxic Peptide (p-BthTX-I)(2) and Its Serum Degradation Product against Multidrug-Resistant Bacteria. Molecules, v. 22, n. 11, . Web of Science Citations: 2. (13/07600-3, 14/05538-1)

CESPEDES, GRAZIELY F.; NOBRE, THATYANE M.; OLIVEIRA, OSVALDO N.; BONG, DENNIS; CILLI, EDUARDO M.. On the role of surrounding regions in the fusion peptide in dengue virus infection. VIROLOGY, v. 557, p. 62-69, . Web of Science Citations: 0. (13/07600-3, 18/22214-6, 13/50319-3, 10/06526-6)

COSTA, NATALIA C. S.; PICCOLI, JULIA P.; SANTOS-FILHO, NORIVAL A.; CLEMENTINO, LEANDRO C.; FUSCO-ALMEIDA, ANA M.; DE ANNUNZIO, SARAH R.; FONTANA, CARLA R.; VERGA, JULIANE B. M.; ETO, SILAS F.; PIZAURO-JUNIOR, JOAO M.; et al. Antimicrobial activity of RP-1 peptide conjugate with ferrocene group. PLoS One, v. 15, n. 3, . Web of Science Citations: 0. (18/11384-8, 13/07600-3)

LORENZON, E. N.; RISKE, K. A.; TROIANO, G. F.; DA HORA, G. C. A.; SOARES, T. A.; CILLI, E. M.. Effect of dimerization on the mechanism of action of aurein 1.2. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, v. 1858, n. 6, p. 1129-1138, . Web of Science Citations: 7. (12/10442-8, 12/15346-7)

DE BARROS, NATAN ROBERTO; ROMEIRO MIRANDA, MATHEUS CARLOS; BORGES, FELIPE AZEVEDO; DE MENDONCA, RICARDO JOSE; CILLI, EDUARDO MAFFUD; HERCULANO, RONDINELLI DONIZETTI. Oxytocin Sustained Release Using Natural Rubber Latex Membranes. INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, v. 22, n. 4, p. 435-444, . Web of Science Citations: 12. (15/02343-8, 14/17526-8)

MIRANDA, M. C. R.; BORGES, F. A.; BARROS, N. R.; SANTOS FILHO, N. A.; MENDONCA, R. J.; HERCULANO, R. D.; CILLI, E. M.. Evaluation of peptides release using a natural rubber latex biomembrane as a carrier. Amino Acids, v. 50, n. 5, p. 503-511, . Web of Science Citations: 3. (15/02343-8, 11/17411-8, 12/15346-7)

LORENZON, ESTEBAN N.; PICCOLI, JULIA P.; SANTOS-FILHO, NORIVAL A.; CILLI, EDUARDO M.. Dimerizatiori of Antimicrobial Peptides: A Promising Strategy to Enhance Antimicrobial Peptide Activity. PROTEIN AND PEPTIDE LETTERS, v. 26, n. 2, p. 98-107, . Web of Science Citations: 1. (13/07600-3, 12/15346-7)

SUELEM D. RAMALHO; MERI EMILI F. PINTO; RENATA K. ANDRICOPULO; PAULO R. S. SANCHES; EDILBERTO R. SILVEIRA; EDUARDO M. CILLI; ADRIANO D. ANDRICOPULO; VANDERLAN S. BOLZANI. Linear Peptide Analogues from Jatropha’s Orbitides Promote Migration of Human Neonatal Foreskin Fibroblasts in vitro and Collagen Deposition. Journal of the Brazilian Chemical Society, v. 30, n. 10, p. 2153-2161, . (15/09533-7, 17/17098-4, 13/07600-3)

RAMALHO, SUELEM D.; PINTO, MERI EMILI F.; ANDRICOPULO, RENATA K.; SANCHES, PAULO R. S.; SILVEIRA, EDILBERTO R.; CILLI, EDUARDO M.; ANDRICOPULO, ADRIANO D.; BOLZANI, VANDERLAN S.. Linear Peptide Analogues from Jatropha's Orbitides Promote Migration of Human Neonatal Foreskin Fibroblasts in vitro and Collagen Deposition. Journal of the Brazilian Chemical Society, v. 30, n. 10, SI, p. 2153-2161, . Web of Science Citations: 0. (15/09533-7, 17/17098-4, 13/07600-3)

ROS, URIS; CARRETERO, GUSTAVO P. B.; PAULINO, JOANA; CRUSCA, JR., EDSON; PAZOS, FABIOLA; CILLI, EDUARDO M.; LANIO, MARIA E.; SCHREIER, SHIRLEY; ALVAREZ, CARLOS. Self-association and folding in membrane determine the mode of action of peptides from the lytic segment of sticholysins. Biochimie, v. 156, p. 109-117, . Web of Science Citations: 1.

DE OLIVEIRA, ALINE LIMA; CILLI, EDUARDO MAFFUD; ROS, URIS; CRUSCA, JR., EDSON; LANIO, MARIA ELIANA; ALVAREZ, CARLOS; SCHREIER, SHIRLEY; PERTINHEZ, THELMA AGUIAR; SPISNI, ALBERTO. Insights on the structure-activity relationship of peptides derived from Sticholysin II. PEPTIDE SCIENCE, v. 110, n. 5, SI, . Web of Science Citations: 1.

SANTOS, ADRIANO; BUENO, PAULO R.; DAVIS, JASON J.. A dual marker label free electrochemical assay for Flavivirus dengue diagnosis. BIOSENSORS & BIOELECTRONICS, v. 100, p. 519-525, . Web of Science Citations: 6. (12/22820-7)

CAIAFFA, KARINA SAMPAIO; MASSUNARI, LOIANE; DANELON, MARCELLE; ABUNA, GABRIEL FLORES; LOMBARDO BEDRAN, TELMA BLANCA; SANTOS-FILHO, NORIVAL ALVES; PALOMARI SPOLIDORIO, DENISE MADALENA; VIZOTO, NATALIA LEAL; CILLI, EDUARDO MAFFUD; DUQUE, CRISTIANE. KR-12-a5 is a non-cytotoxic agent with potent antimicrobial effects against oral pathogens. BIOFOULING, v. 33, n. 10, p. 807-818, . Web of Science Citations: 5. (13/24606-5, 12/15346-7)

VICENTE, EDUARDO F.; SAHU, INDRA D.; CRUSCA, JR., EDSON; BASSO, LUIS G. M.; MUNTE, CLAUDIA E.; COSTA-FILHO, ANTONIO J.; LORIGAN, GARY A.; CILLI, EDUARDO M.. HsDHODH Microdomain-Membrane Interactions Influenced by the Lipid Composition. Journal of Physical Chemistry B, v. 121, n. 49, p. 11085-11095, . Web of Science Citations: 1. (14/00206-0, 10/06526-6, 10/12953-4, 15/18390-5)

LORENZON, ESTEBAN N.; SANTOS-FILHO, NORIVAL A.; RAMOS, MATHEUS A. S.; BAUAB, TAIS M.; CAMARGO, ILANA L. B. C.; CILLI, EDUARDO M.. C-terminal Lysine-Linked Magainin 2 with Increased Activity Against Multidrug-Resistant Bacteria. PROTEIN AND PEPTIDE LETTERS, v. 23, n. 8, p. 738-747, . Web of Science Citations: 6. (13/07600-3, 12/15346-7)

SANTOS-FILHO, NORIVAL A.; LORENZON, ESTEBAN N.; RAMOS, MATHEUS A. S.; SANTOS, CLAUDIA T.; PICCOLI, JULIA P.; BAUAB, TAIS M.; FUSCO-ALMEIDA, ANA M.; CILLI, EDUARDO M.. Synthesis and characterization of an antibacterial and non-toxic dimeric peptide derived from the C-terminal region of Bothropstoxin-I. Toxicon, v. 103, p. 160-168, . Web of Science Citations: 14. (14/05538-1)

SANTOS-FILHO, NORIVAL A.; BOLDRINI-FRANCA, JOHARA; SANTOS-SILVA, LUDIER K.; MENALDO, DANILO L.; HENRIQUE-SILVA, FLAVIO; SOUSA, TIAGO S.; CINTRA, ADELIA C. O.; MAMEDE, CARLA C. N.; OLIVEIRA, FABIO; ARANTES, ELIANE C.; et al. Heterologous expression and biochemical and functional characterization of a recombinant alpha-type myotoxin inhibitor from Bothrops alternatus snake. Biochimie, v. 105, p. 119-128, . Web of Science Citations: 9. (11/23236-4, 08/10760-4)

VICENTE, EDUARDO F.; SAHU, INDRA D.; COSTA-FILHO, ANTONIO J.; CILLI, EDUARDO M.; LORIGAN, GARY A.. Conformational changes of the HsDHODH N-terminal Microdomain via DEER Spectroscopy. Journal of Physical Chemistry B, v. 119, n. 28, p. 8693-8697, . Web of Science Citations: 5. (10/06526-6)

VALLI, MARILIA; RUSSO, HELENA MANNOCHIO; PILON, ALAN CESAR; FERREIRA PINTO, MERI EMILI; DIAS, NATHALIA B.; FREIRE, RAFAEL TEIXEIRA; CASTRO-GAMBOA, IAN; BOLZANI, VANDERLAN DA SILVA. Computational methods for NMR and MS for structure elucidation II: database resources and advanced methods. PHYSICAL SCIENCES REVIEWS, v. 4, n. 11, . Web of Science Citations: 1. (16/13292-8, 17/17098-4, 13/07600-3, 14/50926-0)

PINTO, MERI EMILI F.; NAJAS, JHENNY Z. G.; MAGALHAES, LUMA G.; BOBEY, ANTONIO F.; MENDONCA, JACQUELINE N.; LOPES, NORBERTO P.; LEME, FLAVIA M.; TEIXEIRA, SIMONE P.; TROVO, MARCELO; ANDRICOPULO, ADRIANO D.; et al. Inhibition of Breast Cancer Cell Migration by Cyclotides Isolated from Pombalia calceolaria. Journal of Natural Products, v. 81, n. 5, p. 1203-1208, . Web of Science Citations: 6. (14/50265-3, 17/17098-4, 13/07600-3)

MIRANDA, M. C. R.; PREZOTTI, F. G.; BORGES, F. A.; BARROS, N. R.; CURY, B. S. F.; HERCULANO, R. D.; CILLI, E. M.. Porosity effects of natural latex (Hevea brasiliensis) on release of compounds for biomedical applications. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, v. 28, n. 18, p. 2117-2130, . Web of Science Citations: 7. (15/02343-8, 11/17411-8, 12/15346-7)

RETZL, BERNHARD; HELLINGER, ROLAND; MURATSPAHIC, EDIN; PINTO, MERI E. F.; BOLZANI, VANDERLAN S.; GRUBER, CHRISTIAN W.. Discovery of a Beetroot Protease Inhibitor to Identify and Classify Plant-Derived Cystine Knot Peptides. Journal of Natural Products, v. 83, n. 11, p. 3305-3314, . Web of Science Citations: 0. (19/04381-5)

PICCOLI, JULIA; HEIN, ROBERT; EL-SAGHEER, AFAF H.; BROWN, TOM; CILLI, EDUARDO M.; BUENO, PAULO R.; DAVIS, JASON J.. Redox Capacitive Assaying of C-Reactive Protein at a Peptide Supported Aptamer Interface. Analytical Chemistry, v. 90, n. 5, p. 3005-3008, . Web of Science Citations: 13. (15/02343-8, 13/07600-3, 12/22820-7)

PINHEIRO-JUNIOR, ERNESTO LOPES; BOLDRINI-FRANCA, JOHARA; PIRES DE CAMPOS ARAUJO, LUCIANA MATTOSO; SANTOS-FILHO, NORIVAL ALVES; BENDHACK, LUSIANE MARIA; CILLI, EDUARDO MAFFUD; ARANTES, ELIANE CANDIANI. LmrBPP9: A synthetic bradykinin-potentiating peptide from Lachesis muta rhombeata venom that inhibits the angiotensin-converting enzyme activity in vitro and reduces the blood pressure of hypertensive rats. Peptides, v. 102, p. 1-7, . Web of Science Citations: 4. (14/16182-3, 13/07600-3, 14/05538-1)

BASSO, LUIS G. M.; VICENTE, EDUARDO F.; CRUSCA, JR., EDSON; CILLI, EDUARDO M.; COSTA-FILHO, ANTONIO J.. SARS-CoV fusion peptides induce membrane surface ordering and curvature. SCIENTIFIC REPORTS, v. 6, . Web of Science Citations: 9. (08/57910-0, 14/00206-0, 09/10997-7, 15/18390-5, 10/12953-4)

BOBEY, ANTONIO FERNANDEZ; FERREIRA PINTO, MERI EMILI; CILLI, EDUARDO MAFFUD; LOPES, NORBERTO PEPORINE; BOLZANI, VANDERLAN DA SILVA. A Cyclotide Isolated from Noisettia orchidiflora (Violaceae). Planta Medica, v. 84, n. 12-13, SI, p. 947+, . Web of Science Citations: 1. (14/50926-0, 17/17098-4, 13/07600-3)

INUI KISHI, ROSANGELA NAOMI; STACH-MACHADO, DAGMAR; SINGULANI, JUNYA DE LACORTE; DOS SANTOS, CLAUDIA TAVARES; FUSCO-ALMEIDA, ANA MARISA; CILLI, EDUARDO MAFFUD; FREITAS-ASTUA, JULIANA; PICCHI, SIMONE CRISTINA; MACHADO, MARCOS ANTONIO. Evaluation of cytotoxicity features of antimicrobial peptides with potential to control bacterial diseases of citrus. PLoS One, v. 13, n. 9, . Web of Science Citations: 3. (10/11072-4, 08/52691-9, 12/15346-7)

BATISTA, MARIANA NOGUEIRA; DA SILVA SANCHES, PAULO RICARDO; CARNEIRO, BRUNO MOREIRA; SILVA BRAGA, ANA CLAUDIA; FERNANDES CAMPOS, GUILHERME RODRIGUES; CHILLI, EDUARDO MAFFUD; RAHAL, PAULA. GA-Hecate antiviral properties on HCV whole cycle represent a new antiviral class and open the door for the development of broad spectrum antivirals. SCIENTIFIC REPORTS, v. 8, . Web of Science Citations: 0. (17/00287-9, 16/02174-4, 13/07600-3, 15/23244-8)

VICENTE, EDUARDO F.; BASSO, LUIS GUILHERME M.; CESPEDES, GRAZIELY F.; LORENZON, ESTEBAN N.; CASTRO, MARIANA S.; MENDES-GIANNINI, MARIA JOSE S.; JOSE COSTA-FILHO, ANTONIO; CILLI, EDUARDO M.. Dynamics and Conformational Studies of TOAC Spin Labeled Analogues of Ctx(Ile(21))-Ha Peptide from Hypsiboas albopunctatus. PLoS One, v. 8, n. 4, . Web of Science Citations: 13. (09/10997-7, 10/17662-8, 10/06526-6)

BATISTA, MARIANA NOGUEIRA; DA SILVA SANCHES, PAULO RICARDO; CARNEIRO, BRUNO MOREIRA; SILVA BRAGA, ANA CLAUDIA; FERNANDES CAMPOS, GUILHERME RODRIGUES; CHILLI, EDUARDO MAFFUD; RAHAL, PAULA. GA-Hecate antiviral properties on HCV whole cycle represent a new antiviral class and open the door for the development of broad spectrum antivirals. SCIENTIFIC REPORTS, v. 8, . Web of Science Citations: 0. (17/00287-9, 16/02174-4, 13/07600-3, 15/23244-8)

VICENTE, EDUARDO F.; BASSO, LUIS GUILHERME M.; CESPEDES, GRAZIELY F.; LORENZON, ESTEBAN N.; CASTRO, MARIANA S.; MENDES-GIANNINI, MARIA JOSE S.; JOSE COSTA-FILHO, ANTONIO; CILLI, EDUARDO M.. Dynamics and Conformational Studies of TOAC Spin Labeled Analogues of Ctx(Ile(21))-Ha Peptide from Hypsiboas albopunctatus. PLoS One, v. 8, n. 4, . Web of Science Citations: 13. (09/10997-7, 10/17662-8, 10/06526-6)

LORENZON, ESTEBAN N.; PICCOLI, JULIA P.; CILLI, EDUARDO M.. Interaction between the antimicrobial peptide Aurein 1.2 dimer and mannans. Amino Acids, v. 46, n. 11, p. 2627-2631, . Web of Science Citations: 8. (12/15346-7)

QUEIROZ, SUZANA APARECIDA S.; PINTO, MERI EMILI F.; BOBEY, ANTONIO F.; RUSSO, HELENA M.; BATISTA, ANDREA N. L.; BATISTA, JR., JOAO M.; CODO, ANA C.; MEDEIROS, ALEXANDRA I.; BOLZANI, VANDERLAN S.. Diterpenoids with inhibitory activity of nitrite production from Croton floribundus. Journal of Ethnopharmacology, v. 249, . Web of Science Citations: 0. (19/04381-5, 13/07600-3, 14/25222-9, 17/19870-6, 17/18807-9, 14/50926-0, 17/17098-4)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

CESPEDES, Graziely Ferreira. Sínteses e estudos dos diferentes peptídeos de fusão dos flavivirus causadores da dengue.  112 f. Tese (Doutorado) -  Universidade Estadual Paulista "Júlio de Mesquita Filho" Instituto de Quimica.  (09/15183-8

Patent applications

PEPTÍDEO SINTÉTICO DIMÉRICO ANTIMICROBIANO E ANTIFÚNGICO E SEUS USOS BR1020140217614 - Universidade Estadual Paulista (UNESP). Esteban Nicolás Lorenzon; Eduardo Maffud Cilli; Matheus Aparecido dos Santos Ramos; Taís Maria Bauab - September 2014, 03

PROCESSO DE OBTENÇÃO DE PEPTÍDEOS DIMÉRICOS (p-BthTX-I)2, PEPTÍDEOS DIMÉRICOS (p-BthTX-I)2 E SEU USO COMO ANTIMICROBIANO BR1020140315829 - Universidade Estadual Paulista (UNESP). Esteban Nicolás Lorenzón; Eduardo Maffud Cilli; Matheus Aparecido dos Santos Ramos; Norival Alves Santos Filho; Taís Maria Bauab - December 2014, 17

PROCESSO DE OBTENÇÃO DE MEMBRANA POROSA DE LÁTEX NATURAL, MEMBRANA POROSA DE LÁTEX NATURAL E SEUS USOS BR1020150320477 - Universidade Estadual Paulista (UNESP). Eduardo Maffud Cilli; Rondinelli Donizetti Herculano; Matheus Carlos Romeiro Miranda - December 2015, 21

Solicitação em análise e dentro do prazo legal de sigilo previsto na legislação BR1020180719149 - Universidade Estadual Paulista (UNESP). Solicitação em análise e dentro do prazo legal de sigilo previsto na legislação - October 2018, 24

Solicitação em análise e dentro do prazo legal de sigilo previsto na legislação PCT/BR2016/050337 - Universidade Estadual Paulista (UNESP). Solicitação em análise e dentro do prazo legal de sigilo previsto na legislação - December 2016, 19

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