Abstract
Leishmania spp. are the causative agents of Leishmaniasis, a disease that affects millions of people worldwide. Several studies have demonstrated that these parasites may engage Pattern-recognition receptors (PRRs), such as Toll-like receptors (TLRs) and Nod-like receptors (NLRs). In the latter case, activation of the NLRP3 inflammasome by Leishmania spp. has been demonstrated by many gro…