- Research Grants
bachelor's at Biomedical Sciences at Universidade Estadual Paulista Júlio de Mesquita Filho (2002), master's (2005) and doctorate (2009) at Sciences with emphasis in Cancerology from Fundação Antônio Prudente. Actually, Mariana is a research associate at University College Londonl. Has experience in molecular biology, genetics and genomics, focusing on Human and Medical Genetics. (Source: Lattes Curriculum)
Pediatric solid tumors comprise 3% of all cancers with approximately 70% of these children becoming adults. The treatment of tumors with poorer prognosis has already reached the limits of tolerance requiring the search for alternative therapies. On the other hand, around one in every 750-1000 adults are survivors of cancer in the childhood and suffer late adverse effects from the aggres...
The embryonic Wilms tumors are tumors that exhibit morphological heterogeneity with three components: blastema, epithelia and stroma. Mutations in WT1, CTNNB1, WTX, DROSHA, SIX2, MYCN, TP53, and others less common genes overlap and are found in 30% of the analyzed cases. Moreover, the loss of imprinting of 11p15, resulting in overexpression of IGF2 is found in about 70% of cases. Alone,...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|