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Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Médicas (FCM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Rodrigo Bueno de Oliveira in research grants and scholarships supported by FAPESP.
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Introduction: osteoporosis is a disease characterized by a decrease in the mineral density of bones and this condition makes them more fragile and susceptible to fractures. Although this pathology is relatively well understood, there is a gap in the literature when referring to the influence of microplastics (MPs) on the development of osteoporosis. Aim: analyse the influence of polystyre…
One of the biggest health challenges in the world is to reduce cardiovascular complications in patients with chronic kidney disease (CKD). Recent evidence has shown that gliflozins are associated with a 30% reduction in the risk of death and progression of mild/moderate CKD. Experimental data suggest that gliflozins may positively interfere with serum Klotho concentration. The potential e…
Chronic kidney disease (CKD) is associated with mineral and bone disorders (MBD) and cardiovascular disease (CVD), common complications of CKD. Advanced glycosylation end-products (AGEs) are involved with CVD and CKD-MBD, however, pathophysiology still poorly understood. AGEs have potential to be used as a marker of tissue damage or therapeutic target. A non-invasive instrument (AGE-Reade…
Introduction: Experimental data show that polystyrene, a type of microplastic (MP), is implicated in the reduction of bone mass, number of trabeculae and its increased spacing, in addition to the reduction of the size of long bones in pubertal mice, through the acceleration of osteoblast senescence, by the reduction of the expression of the Runx2 gene, among other factors. Recently, it wa…
Introduction: Environmental contamination by microplastics (MP), plastic particles with a diameter of less than 5 mm, is a growing concern due to their ubiquity, particularly polystyrene, a common type of MP found in the environment. Several studies have documented the adverse effects of PS on mitochondrial dysfunction in different cells, including cells from the cardiovascular, renal and…
Microplastics (MP) are plastic fibers < 5 mm in diameter. Currently, it is considered the most relevant synthetic contaminant on the surface of the planet. Evidence indicates that MP interacts negatively with biological structures. For example, the presence of MP has been demonstrated in bone marrow, with negative effects. In an animal model, MP was associated with activation of the Wnt/²…
Introduction: Secondary hyperparathyroidism (SPH) is characterized by high levelsserum levels of parathyroid hormone (PTH) due to chronic kidney disease (CKD). The treatmentSurgical surgery (parathyroidectomy, PTx) is considered as a therapeutic option when HPS isrefractory to clinical therapy. The literature suggests reciprocal effects of PTH variations onserum catecholamines and these o…
| 2 / 2 | Ongoing grants |
| 1 / 1 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 3 / 2 | Completed scholarships in Brazil |
| 9 / 8 | All research grants and scholarships |
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