CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Faculdade de Odontologia (FOA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Associate Professor of Endodontics at the School of Dentistry of Araçatuba (FOA-Unesp) and Lead Researcher of the CNPq research group: Nucleus of studies in Endodontic Medicine: interrelationship between apical periodontitis, systemic disorders and the response of materials. Dentist graduated from FOA-Unesp (2000); Specialist in Endodontics - FOA-Unesp (2002); Master in Dentistry, Endodontics - Faculty of Dentistry of Bauru - FOB-USP (2005); PhD in Clinical Dentistry, Endodontics, Faculty of Dentistry of Piracicaba - FOP-Unicamp (2008); Post-Doctorate at the State University of Maringá - UEM (2011); Associate Professor at FOA-Unesp (2014); Vice-Coordinator (2013-2015) and Coordinator (2015-2021) of the Stricto Sensu Graduate Program (Master's and Doctorate in Science - 6 Capes Concept); MBA in Management from Fundação Getúlio Vargas - FGV (2022). He currently serves as Vice-Director of the Faculty of Dentistry of Araçatuba - Unesp and Coordinator of Lato Sensu Graduate Studies (Specialization in Endodontics). It has H Factor 35 (Web of Science) and 39 (Scopus); He has published 295 articles, 1 book and 30 book chapters. (Source: Lattes Curriculum)
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The Institutional Reserve Application Plan to Support the Research Infrastructure of the Araçatuba School of Dentistry (FOA) aims to encourage the sharing of research infrastructure among faculty, research groups, and graduate programs, thereby maintaining quality and increasing scientific productivity.Considering MCTI Ordinance No. 9,037/2025, which establishes the licensing of activitie…
The interrelationship between systemic disease and the development and progression of oral infections such as apical periodontitis has been the subject of intense study in recent years, especially by our research group. The aim of this study is to evaluate the interrelationship between apical periodontitis (AP) associated with liver fibrosis (LF) through the study of NLRP3 inflammasome, I…
Tissue reactions against new filling materials should be checked earlier in subcutaneous connective tissue (ISO 10993-6. 2007), and biocompatibility can be observed by staining hematoxila and eosin (HE) (Cintra et al., 2006, 2010, 2012, Gomes-Filho et al., 2008, 2009, 2011). Moreover, the use of immunohistochemical technique offers the possibility of understanding the cellular and molecul…
(Only some records are available in English at this moment)
Dental bleaching with hydrogen peroxide (H2O2) is widely used in dental practice to improve dental aesthetics but can trigger inflammatory responses in the pulp tissue of varying intensities. This study aims to investigate the inflammatory and reparative responses of the pulp tissue in rat molars subjected to dental bleaching using new gel formulations containing H¿O¿ combined with biomod…
Osteomyelitis (OM) is a multifactorial disease characterized by inflammatory and infectious events of bone tissue with systemic repercussions, associated with poor prognosis when concomitant or after orthopedic surgical procedures, constituting a significant therapeutic challenge. Apical periodontitis (AP) also affects bone tissue at the alveolar level and has an inflammatory and resorpti…
Apical periodontitis (AP) is characterized by inflammation and periapical bone resorption caused by bacterial colonization in root canal systems. Diabetes Mellitus (DM) is a metabolic disease characterized by hyperglycemia caused by insulin resistance and/or insulin secretion deficiency. Previous studies by our research group have shown that DM can accelerate the development and severity …
Apical periodontitis (AP) is characterized as an inflammatory disease of theperiradicular tissues originating from endodontic infections. Diabetes Mellitus (DM) isa disorder present in a high proportion of the world's population, characterized as agroup of metabolic diseases marked by hyperglycemia due to insulin resistance. Thepresence of this chronic hyperglycemia is related to systemic…
Introduction: The home bleaching technique has been used frequently due to the comfort and lower concentration of active ingredients in hydrogen peroxide-based or carbamide peroxide (CP)-based gels. In addition, new bleaching products have been developed, such as sodium dithionite (Dit)-based bleaching tape. However, previous studies have shown that tooth bleaching can induce an inflammat…
Apical periodontitis (AP) is an inflammatory response resulting from bacterial infection of the root canals, which, over time, can cause bone destruction of the periapical tissues. Studies have demonstrated the potential of AP to exacerbate systemic inflammatory responses, especially in the presence of multiple foci of infection. The objective of this study is to analyze different blood p…
(Only some records are available in English at this moment)
Regenerative endodontics is advancing modern dentistry by restoring the root canals to a healthy state, allowing for continued development of the root and surrounding tissue. GelMA hydrogels, noted for their tunable mechanical properties and injectability, are ideal for incorporating therapeutic agents like curcumin, which offers anti-inflammatory and antimicrobial benefits. Adding Minera…
The presence of microorganisms inside root canals is responsible for activating the immune system through an inflammatory process. However, if this inflammatory process persists, leading to irreversible inflammation, pulp necrosis and the possible presence of apical periodontitis (AP), root canal treatment becomes necessary. Endodontic diseases, such as AP, are responsible for the systemi…
Apical periodontitis (AP) is characterized by pulp necrosis leading to periapical bone degradation, consequence of bacterial colonization of root canals. It is a serious public health problem, because there is a bidirectional relationship between oral infections and systemic health. Endodontic medicine seeks to investigate alternative therapy options against this disease, in which herbal …
Periapical periodontitis is an infectious disease characterized by inammatory bone destruction that is mediated by bacteria-reactive lymphocytes. A growing body of evidence supports that osteoclastogenesis factor, receptor activator of nuclear factor kappa B (NF-kB) ligand (RANKL), produced by activated lymphocytes is responsible for the induction of bone resorption in periapical periodon…