graduation at Ciências Fundamentais da Saúde from Universidade de São Paulo (2009) and doctorate at Physiology from Universidade de São Paulo (2014). Has experience in Biochemistry, focusing on Molecular Biology (Source: Lattes Curriculum)
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Diabetic Kidney Disease (DKD) and Focal and Segmental Glomerulosclerosis (FSGS) are the main causes of Chronic Kidney Disease (CKD), a condition characterized by progressive loss of renal function and the presence of proteins in the urine. The loss of proteins is closely associated with the dysfunction of podocytes, highly specialized cells that make up the glomerular filtration barrier. …
Diabetic kidney disease (DKD) is a complication that develops in approximately 40% of patients with type 2 diabetes mellitus (T2DM) and represents one of the main causes of progression to chronic kidney disease (CKD). It is known that inflammation, both systemic and local, plays an important role in the development of DKD. Macrophages are among the main types of immune cells present in ki…
Chronic Kidney Disease (CKD) is a clinical condition characterized by progressive loss of kidney function and persistent presence of proteins in the urine. Among the causes that can lead to CKD are glomerulopathies, especially Focal Segmental Glomerulosclerosis (FSGS). Loss of protein in the urine and development of FSGS is closely associated with dysfunction and loss of podocytes, specia…
Diabetic kidney disease (DKD) is the leading cause of end stage kidney disease in the world. Currently, treatments are mainly based on blood glucose and blood pressure control, but clinical studies suggest that they have a mild or neutral positive effect on the progression of DKD once renal dysfunction has already been established. Hyperglycemia, one of the main supporting elements in the…
Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease. Type 1 and type 2 diabetes lead to the development of DKD, however, the growth in the number of individuals with obesity and type 2 diabetes has been a major contributor to the increase in the prevalence, incidence and number of deaths from chronic kidney disease. The understanding of the mechanisms that produc…
Diabetes mellitus (DM) is the major cause of chronic kidney disease in the world and glomerular dysfunction is the most common etiologic factor for kidney function loss. Hyperglycemia participates in the development of diabetic nephropathy (DN), among other pathways, through the increased production of advanced glycation end products (AGEs). However only a few studies have evaluated the e…
The overall scope of the problem is that as the US population lives longer, kidney disease becomes more abundant. Elderly patients in particular face worse disease outcomes and they are now the largest group to undergo first-time dialysis. The goal of this proposal is to prove that aged terminally differentiated glomerular epithelial cells, called podocytes, are central to the many glomer…
Introduction: Diabetic nephropathy (DN) is the most common cause of endstage renal disease worldwide and new therapies are urgently needed. The studies focusing in new mechanistic insights into the (patho)physiology of renal injury in diabetes, as well as potentially leading to the development of novel therapeutic interventions in DN, through targeting non-coding RNA-regulated epigenetic …
| 1 / 1 | Ongoing research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 5 / 3 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 10 / 8 | All research grants and scholarships |
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CV Lattes
ORCID