Resumo
Immunotherapy with Bacillus Calmette-Guerin (BCG) has been the gold standard treatment for non-muscle invasive bladder cancer (NMIBC) for almost half a century. However, many high-risk disease patients experience recurrence, including those who progress and eventually do not respond to BCG. For decades, apart from radical cystectomy, few therapeutic options existed for this high-risk popu…