CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Postdoctoral research in progress in respiratory physiology at the Ribeirão Preto Medical School (FMRP-USP). Holds a PhD in human physiology from the University of São Paulo (USP) with a sandwich period completed at University College London (UCL). Masters in biological sciences and undergraduate degree in physical education from the Federal University of Ouro Preto (UFOP). Has experience with genetically modified animals, optogenetics, chemogenetics, and morphofunctional analysis of glia as well as its interrelation with neural cardiovascular and respiratory control. (Source: Lattes Curriculum)
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Astrocytes play an important role in controlling neuronal excitability by modulating synaptic transmission through the release of signaling molecules or "gliotransmitters". Several studies suggest that astrocytes can influence neural circuits controlling different physiological functions. However, it is still not well defined whether astrocytes can directly modulate neural networks involv…
Hyperosmolality is an imbalance of homeostatic control of osmolality mainly due to an elevation of the sodium concentration in the extracellular milieu. It is well established that increasing in osmolality, due to a salt loading, leads to rise in the blood pressure associated to a simpathoexcitation at the PVN neuronal level. Recent observations from our laboratory have shown that ATP, ac…
Preliminary data from my PhD project have shown that salt-sensitive neurogenic hypertension elicits an increased in the mRNA level of the ectonucleotidase triphosphate diphosphohydrolase 3 (E-NTPD3) in the hypothalamic paraventricular nucleus (PVN). This enzyme hydrolyses ATP to ADP and ADP to AMP, and increase the concentration of a substrate of ecto-5'-nucleotidase (AMP) to produce aden…
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