CV Lattes
ResearcherID
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduation at Educação Física from Universidade Federal de Viçosa (2008), master's at General Biology from Universidade Federal de Viçosa (2010) and doctorate at Fitness from Universidade de São Paulo (2015). (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| TITULO |
| Articles published in other media outlets (0 total): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Physical inactivity is considered one of the main factors for the increase in the incidence of chronic-degenerative diseases. The benefits of physical exercise are directly linked to the improvement of mitochondrial bioenergetic input. Recently, we demonstrated that the optimization of cardiac mitochondrial metabolism in physical exercise is associated to the degree of mitochondrial plast…
Doxorubicin is a potent and widely used antineoplastic agent. However, almost 30% of patients treated with doxorubicin develop heart failure. The mechanism behind its cardiotoxic effect is elusive. Recent evidence suggests that doxorubicin accumulates in cardiac mitochondria causing both mutations and reduction in number of mitochondrial DNA copies. This scenario reduces the expression of…
Doxorubicin is an anthracycline widely used to treat different types of cancer including leukemia, lymphomas and breast cancer. However, it has high risk of cardiotoxicity since it accumulates and negatively affects cardiac mitochondrial proteostasis and bioenergetics. Disruption of mitochondrial proteostasis triggers a conserved signaling pathway termed mitochondrial unfolded protein res…
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 3 / 3 | All Scholarships |
| Associated processes | |