CV Lattes
ORCID
Abstract
Experimental autoimmune encephalomyelitis (EAE) serves as experimental model of multiple sclerosis (MS) since both diseases share clinical and histopathological similarities. EAE is a CD4+ T cell-mediated autoimmune disease. Although it is clear that encephalitogenic CD4+ T cells perform a proinflammatory activity, how these T helper cells are able to exert effector role during the clinic…