CV Lattes
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ORCID
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Has experience in Microbiology, focusing on Microbiology (Source: Lattes Curriculum)
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In human cells, mitochondrial respiratory complexes and mitoribosomes are the only examples of protein clusters whose formation derives from two distinct genomes. In order to achieve stoichiometric balance between the products of nuclear and mitochondrial origin, mitochondrial gene expression is finely controlled by a series of factors of nuclear origin, thus avoiding not only unnecessary…
The translation of mitochondrially encoded mRNAs is done by mitoribosomes. Mitochondrial translation involves several factors, including translation activators, which bind to a site in the 5 'UTR region of the mitochondrial mRNA and a site in the coding region. The factors Pet309, Pet111 and Pet494 have already been observed for the COX1, COX2 and COX3 genes, respectively. Several unchara…
mRNA translation requires the correct association of the tRNA with the cognate aminoacid. This process is carried by a specific aminoacyl-tRNA synthase. Some bacteria and organelles do not have the complete of aminoacyl tRNA synthases and extra transamidation reactions are therefore required for the aminoacid inespecifically associated to the tRNA. For instance this process occurs in the …
In Saccharomyces cerevisiae, the mitochondrial DNA (mtDNA) is responsible for coding seven proteins that are subunits of the OXPHOS complexes. Cox2p, encoded by the mtDNA, is one of the proteins comprising the catalytic core of cytochrome c oxidase, and it is associated with two atoms of copper (CuA center). Cox2p has two transmembrane domains that count on several proteins to be correctl…
| 1 / 1 | Ongoing scholarships in Brazil |
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
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