CV Lattes
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Universidade de São Paulo (USP). Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Química Industrial from Universidade de Ribeirão Preto (1988), master's at Chemistry from Universidade de São Paulo (1992) and doctorate at Chemistry from Universidade de São Paulo (1996). Has experience in Chemistry, focusing on Analytical Instrumentation, acting on the following subjects: amostras de plasma, cromatografia líquida de alta eficiência, antidepressivos, microextração em fase sólida and stir-bar sorptive extraction sbse. (Source: Lattes Curriculum)
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The conclusive diagnosis of neurodegenerative diseases, such as Parkinson's disease (PD) and Alzheimer's disease (AD), has been predominantly clinical and, in these cases, the neurodegeneration is already installed in the patient's brain. Therefore, efforts have been made to identify molecular biomarkers for early diagnosis and monitoring these neurodegenerations progression. High perform…
The main motivation behind this proposal is the recognition that a well-exploited association of micro techniques covering sample preparation, chromatography and mass spectrometry exhibits very concrete potential for gains in analytical quality in association with the precepts of green chemistry. Directly, we envisage several advances from fundamental aspects to applications on real sampl…
The National Institute of Translational Medicine (NITM) was created in 2008 with the purpose of establishing a national network of research centers with outstanding experience in the investigation of biomarkers and new therapeutic targets and molecules in neuropsychiatric disorders, acting in the strategic area of Health and Medicines defined by the Federal Government. In the base of all …
(Only some records are available in English at this moment)
Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that affects about 5% of the world population aged over 65 years. Physiopathologically it is characterized by the presence of neurofibrillary tangles (tau proteins) and the accumulation of senile plaques (deposits of beta-amyloid peptides), which result in synaptic loss and neuronal death observed in the brain regions re…
Alzheimer's disease (AD) has been considered one of the main neurodegenerative diseases affecting about 5% of people over than 65 years old. Common symptoms of AD include declining in cognitive and memory skills. Considering the pathophysiology, AD has been characterized by the accumulation of ²-amyloid proteins and TAU microtubulin in senile plaques and neurofibrillary structures. The di…
Alzheimer's disease (AD) is a progressive neurodegenerative dementia that affects about 5% of the world's population over 65 years old. It can also occur in individuals under 40 years of age (AD). AD is pathologically characterized by the presence of neuritic plaques and neurofibrillary tangles. The formation of neuritic plaques is due to the extracellular accumulation of the ²-amyloid pe…
(Only some records are available in English at this moment)
N-arachidonoyl-ethanolamine (AEA) and 2-arachidonoylglycerol (2-AG) are the main representatives of the endocannabinoid (EC) family, a group of neurotransmitters that act in signaling processes by activating the cannabinoid receptors type 1 and type 2 (CB1 and CB2). Given the role that AEA and 2-AG play in synaptic transmissions in the brain, they have been extensively studied as potentia…
Light olefins are essential building blocks in the chemical industry and important byproducts of various chemical processes. Because olefins and paraffins with the same number of carbons have similar volatility and polarity, the separation of olefin/paraffin mixtures is oftentimes challenging. Silver-based ionic liquids (ILs), which were recently developed by Prof. Jared Anderson's group,…
Endocannabinoids (ECs) act on cannabinoid receptors; i.e., CB1 and CB2. The CB1 receptor system then interacts with many neurotransmitters and neuromodulators in the central and peripheral nervous systems in different ways. The multiple roles attributed to ECs make them an emerging target of pharmacotherapy for several disparate diseases. Anandamide (AEA) and 2-arachidonoyl glycerol (2-AG…
| 10 / 6 | Completed research grants |
| 20 / 18 | Completed scholarships in Brazil |
| 3 / 3 | Completed scholarships abroad |
| 33 / 27 | All research grants and scholarships |
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