Abstract
The Bothrops are responsible for about 80 % of reported accidents in Brazil. Bothrops poisoning are described in several places and among these effects is the tissue damage that can result in dysfunction of the affected organ. Two toxins, jararhagin (JAR) and bothropstoxin - I (BthTX - I), isolated from Bothrops jararaca and Bothrops jararacussu, respectively, are involved in intense infl…