CV Lattes
Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated from the University of Mogi das Cruzes in the field of biomedicine. Concluded scientific initiation at the University of São Paulo in the area of cell and molecular biology with studies focused on neurodegeneration, developing three projects aiming to analyze mitophagy in a protein aggregation model associated with neurodegeneration. He is currently developing an academic master's project in the area of human reproduction, with the aim of analyzing spermatic mitophagy after in vitro fertilization at the Federal University of São Paulo. (Source: Lattes Curriculum)
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It has been described that the mechanism of mitophagy is essential to ensure the uniparental transmission of mtDNA and participating in this mitochondrial degradation we find ubiquitin binding proteins such as E3 ubiquitin ligase Parkin. This protein is responsible for the ubiquitination of the proteins presents in the mitochondrial membrane so that they are directed to the proteasomal pr…
It is known that there is accumulation of proteins in the intra- and extracellular environment during aging, and it is believed that the impairment of protein quality contributes to the cellular events that culminate in neurodegeneration. The presence of these protein aggregates leads to intracellular damage including mitochondrial dysfunction, deficiency in its traffic, biogenesis and de…
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