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Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Farmacêuticas (FCF) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Natália Barreto dos Santos in research grants and scholarships supported by FAPESP.
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Gliomas correspond to approximately 80% of primary malignant brain tumors in adults. Until recently, these tumors were classified mainly on the basis of histopathological criteria; however, associating these aspects to the identification of the molecular profile of the neoplasias has been shown to be a more accurate strategy in relation to the prediction of the tumor's behavior and its re…
Malignant gliomas are brain tumors originating from glial cells, mainly of astrocytes. It is a devastating human cancer, whose incidence and mortality are expected to increase in the coming years. The intense cell migration, which results in the high capacity to invade healthy nervous tissue, is one of the characteristics of gliomas that makes its treatment difficult. The RhoA/ROCK pathwa…
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