- Research Grants
graduate at Química from Universidade Federal do Rio de Janeiro (1954) and ph.d. at Chemistry from Universidade de São Paulo (1963). Has experience in Physic, focusing on Liquids and Solids Structure; crystallography, acting on the following subjects: estrutura cristalina, difração de raios-x, método de rietveld, estrutura molecular and cristalografia de raios-x. (Source: Lattes Curriculum)
Our activities along the time of existence of this project will take place in two main areas: a) directly at the school in contact with teachers and students and b) through the Portal Ciência Web (www.cienciaweb.com.br). Thre overall objective of the proj (AU)
(Only some records are available in English at this moment)
Pilocarpine is an alkaloid isolated from the leaves of Pilocarpus microphyllus (Rutaceae), a native plant from Brazil, known as jaborandi, which presents muscarinic agonist activity, and it is used as a miotic agent in the treatment of glaucoma. The alkaloid imidazole Epiisopiloturina (EPI) comprises 70% of purifying residue, with activity against Schistosma mansoni, and other compounds...
Epiisopiloturine is an imidazole alkaloid extracted from Pilocarpus microphyllus Stapf ex Wardleworth, a Brazilian native plant, whose in vivo activity against Schistosoma mansoni led to parasite burden, to reduction in hepatosplenomegaly, the egg burden in faeces, and fell granuloma diameter. Epiisopilosine, another secondary metabolite from jaborandi, was tested in vitro (just accepte...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|