CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
I received my B.S. in Natural History from Pontifícia Universidade Católica do Paraná (1973), M. S. in Cell Biology from Universidade Federal do Paraná (1982) and Ph.D., also in Cell Biology, from Universidade de São Paulo (1986). I did my post-doctoral training at NIH, Bethesda, Md, USA (1991). Currently I am full professor at the University of São Paulo. I have experience in the morphology with an emphasis in cell biology. My research focuses on mast cells, investigating mast cell precursors, recruitment of mast cells from the bone marrow to peripherial tissues, mast cell activation, signal transduction and mediator release. (Source: Lattes Curriculum)
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Mast cells are immunoregulatory cells that are implicated in innate and adaptive immunity. Mast cells participate in different biological events such as host protection, angiogenesis, inflammatory and allergic reactions. The action of mast cells is related directly to their activation and subsequent mediator release. The best characterized mast cell activation pathway is that via the high…
Mast cells are multifunctional cells of the immune system that act in both innate and acquired immunity and in various biological events such as: defense of the organism, angiogenesis and inflammatory and allergic reactions. These actions are directly related to mast cell activation which results in the liberations of diverse chemical mediators. Mast cell activation most commonly occurs …
Our group has regularly investigated the recognition of glycans on host cells by pathogen lectins; we have also studied the biological responses triggered by such recognition. Our team has focused on particular lectins: (i) TgMIC1 and TgMIC4 - proteins secreted by micronemes of the protozoan Toxoplasma gondii that recognize glycans bearing sialic acid and beta-galactose as terminal resid…
(Only some records are available in English at this moment)
RACK1 (Receptor for Activated C Kinase 1) is an adaptor protein expressed in mammal cells and crucial for fundamental cellular activities. The RACK1 has a central role in the immune cells response, integrating signaling pathways, acting in calcium mobilization, and in components of the cytoskeleton. The mast cells are multifunctional effector cells of the immune system and their functions…
Mast cells are immunoregulatory cells that are implicated in innate and adaptive immunity. Mast cells participate in different biological events such as host protection, angiogenesis, inflammatory and allergic reactions. The action of mast cells is related directly to their activation and subsequent mediator release. The best characterized mast cell activation pathway is that via the high…
Mast cells are immunoregulatory cells that participate in various biological events such as host defense, angiogenesis, inflammatory and allergic reactions. These events are directly related to mast cell activation and subsequent mediator release. Mast cell activation generally occurs through the interaction of a multivalent antigen (allergen) with immunoglobulin E (IgE) bound to the high…
(Only some records are available in English at this moment)
Mast cells are immunoregulatory cells that participate in various events such as asthma, allergy, and inflammation. The action of mast cells is directly related to their activation and subsequent release of various chemical mediators. Activation via the high affinity IgE receptor, FcµRI, is the best characterized form of mast cell activation that results in mediator secretion. Mediator re…
| 9 / 6 | Completed research grants |
| 14 / 6 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 24 / 13 | All research grants and scholarships |
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