Undergraduate in Pharmacy from Universidade Federal do Espírito Santo (2008-2014), Master degree in Biochemistry and Pharmacology at Universidade Federal do Espírito Santo (2014- 2016) and PhD degree in Pharmaceutical Sciences at University of São Paulo (USP, Brazil) and PhD degree in Health at Aarhus University (Denmark) (2016-2021). Currently, I am a postdoc at Neuropsychopharmacology Laboratory from the School of Pharmaceutical Sciences of the Ribeirão Preto at the University of São Paulo (USP), focusing on investigating the neurobiology and pharmacological treatment of depressive and anxiety disorders. (Source: Lattes Curriculum)
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Obesity and depressive disorder are considered serious health problems that have high prevalence and morbidity and mortality rates. Obesity is associated with increased prevalence and severity of the depressive disorder, and this association occurs in a bidirectional manner. However, the molecular mechanisms involved in the association of depression with obesity have not been elucidated. …
Depression is a debilitating psychiatric disorder. Antidepressants have limitations on their use, such as the delay of four to six weeks for onset of therapeutic action and inefficiency in 30-45% of patients.Among the substances that present a better therapeutic profile are cannabidiol (CBD), which showed a rapid and sustained antidepressant effect in animal models. The mechanisms respons…
Depression is a debilitating and disabling psychiatric disorder. Dysfunction on pre-frontal cortex (PFC) have been related to depression. Ketamine is an important drug that produces rapid and sustained antidepressant effects, which seems to involve activation of the BDNF-TrkB-mTOR pathway, with subsequent activation of MEK and PI3K, leading to increased synaptogenesis. We have recently sh…
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