Dr. Léa Assed completed the Undergraduate Course in Dentistry at the School of Dentistry of Ribeirão Preto - University of São Paulo (FORP/USP) in 1972. She obtained the title of Specialist in Pediatric Dentistry in 1976 and the title of Specialist in Dentistry for Patients with Special Needs in 2004. Completed her Doctorate in Dental Sciences (Pediatric Dentistry) at the Universidade Estadual Paulista Júlio de Mesquita Filho, in 1991. She is a Full Professor of Pediatric Dentistry at FORP/USP since 1999. She is the leader of the Research Group entitled "Etiology and Treatment Pulp and Periapical Pathologies" in addition to participating in 4 other research groups registered at CNPq. She was Director of FORP / USP (term 2016/2020). She is a CNPq Research Productivity Scholar, Level 1B. Member of the Editorial Board of several periodicals with international circulation and high impact factor. She is an Ad-Hoc advisor for Fapesp, CNPq and Capes. She has published more than 300 scientific articles throughout her university career, in addition to authoring 3 books and several book chapters. She has supervised and guides several Master's, Doctoral and Post-Doctoral students. She is currently Head of the Children's Clinic Department at FORP / USP, Vice-Coordinator of the Postgraduate Program in Pediatric Dentistry (CAPES 6) and Mayor of the USP Ribeirão Preto Campus. (Source: Lattes Curriculum)
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Inflammasome is a multiprotein complex that aim to trigger caspase-1 activation and, consequently, cleave interleukins as IL-1² and IL-18. This complex has been studied in different systemic diseases as therapeutic target. The modulation of inflammasomes components could change or favor the resolution of those diseases. Thus, the aim of this study will be to evaluate the role of NLRP3 inf…
The fundings will be used to refurbish the Animal Care Facility II and to conclude the adequacy of the physical space for the creation of the Integrated Clinical Research Center at FORP/USP. (AU)
(Only some records are available in English at this moment)
The periapical lesion is an inflammatory response to infection in the root canal system.roots, with the participation of different cell types, receptors and ligands during theits development. Pathogen-associated molecular patterns (PAMPs) as well assynthetic ligands such as Pam3Cys, bind to toll-like receptors, such as TLR2,to activate the innate immune system. Regulatory T lymphocytes (T…
Neutrophil extracellular traps (NETs) are one of the ways in which neutrophils act in the host's inflammatory immune response and can lead to exacerbation of tissue damage. At the same time, previous studies have demonstrated the positive effect of probiotics on pulpal infections. However, the effect of probiotics on NETs is still unknown. Thus, the objective of this study will be the mic…
Periapical lesions are the result of the host's immune-inflammatory response to bacterial infections in root canals, fundamentally from caries lesions. Endodontic treatment aims to eliminate pathogenic microorganisms and promote the resolution of inflammation. Conventional irrigating solutions have limitations in the effective elimination of bacteria and in the modulation of the inflammat…
(Only some records are available in English at this moment)
The aim of this study is to evaluate cell behavior induced by sealers Real Seal XT1 and Sealapex Xpress. The cell viability and proliferation will be assessed after exposure of cells to cement Sealapex Spress (group I) and Real Seal XT1 (group II). As a control, cells will be exposed to bacterial endotoxin (LPS) (Group III) and to the DMEM-c culture (Group IV). Cell viability of the suspe…
| 24 / 13 | Completed research grants |
| 14 / 6 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 39 / 20 | All research grants and scholarships |
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CV Lattes
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