Has experience in Chemistry, focusing on Analysis of Traces and Ambient Chemistry (Source: Lattes Curriculum)
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Peroxidasin (PXDN) is a heme-peroxidase expressed mainly at the extracellular matrix of the vascular endothelium. This enzyme catalyzes the oxidation of chloride or bromide by hydrogen peroxide producing the respective hypohalous acid. The products of PXDN oxidize collagen residues forming cross-linked chains at the basement membrane. In spite of this evidence, the physiological function …
Peroxidasin (PXDN) is a heme peroxidase enzyme expressed in the extracellular matrix in several tissues. This enzyme catalyzes the formation of hypobromous acid (HOBr) from H2O2 and bromide. HOBr oxidizes amino acid residues to form covalent sulfilimine bonds in collagen IV in the basement membrane, a unique post-translational modification in biological systems. However, it is still uncle…
Peroxidasin (PXDN) is a heme-peroxidase enzyme expressed in the extracellular matrix in several tissues. This enzyme catalyzes the formation of hypobromous acid (HOBr) from H2O2 and bromide. HOBr oxidizes amino acid residues to form covalent sulfilimine bonds in collagen IV in the basement membrane. This catalytic process displays a unique feature and was the first report of the presence …
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