CV Lattes
Universidade de São Paulo (USP). Instituto de Biociências (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bianca Portela Costa in research grants and scholarships supported by FAPESP.
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In patients affected by Marfan Syndrome (MFS), the synthesis of extracellular matrix microfibrils is impaired by mutations in the FBN1 gene, resulting in a fragile and unstable connective tissue. Thus, the syndrome is characterized for its systemic phenotypic effects, affecting mainly the bone, ocular and cardiovascular tissues, the latter being the most worrying, responsible for life exp…
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