Abstract
The aim of this study will be to evaluate the systemic response, biocompatibility, and bioactive potential and physicochemical properties of a bioceramic-based intracanal medication, BIO-C TEMP in comparison with the Calen paste. Polyethylene tubes will be filled with BIO-C TEMP or Calen paste and will be implanted in the dorsal subcutaneous of sixty male adult rats distributed into 3 gro…