- Research Grants
Rafael is Chief Scientist at the Structural Genomics Consortium laboratory at UNICAMP (SGC-UNICAMP). Trained in biochemistry and protein crystallography, Rafael obtained his PhD from Rice University (TX-USA) in 2005 and worked as a postdoctoral scientist in the US, New Zealand and Australia before joining the SGC-UNICAMP in 2015. Rafael?s primary interests are: 1) identifying and validating potential therapeutic targets for human diseases; and 2) using chemical biology to elucidate protein function. Our lab is fully-equipped and staffed to go from the cloning of a candidate gene to the design and synthesis of highly potent and specific small molecule ligands - called chemical probes. We employ these chemical probes to validate potential therapeutic targets and unlock new biology. Our lab develops chemical probes against human kinases linked to oncology and other human conditions; and against potential drug targets for Neglected and Emerging Infectious Diseases. SGC-UNICAMP is part of OpenMedChem, a CNPq and FAPESP-funded INCT that allows the Brazilian academic community to access our laboratory infrastructure and expertise to advance their own projects. Since 2017, SGC-UNICAMP is also an EMBRAPII (Empresa Brasileira de Pesquisa e Inovação Industrial) unit, providing Brazilian pharma access to cutting edge tools and expertise in structure-based drug discovery and medicinal chemistry. Rafael believes in the power of open science to accelerate discoveries in human health - all SGC-UNICAMP results are made available to the public without delays and we do not seek IP in any of our findings. (Source: Lattes Curriculum)
Many of the discoveries from the rapidly expanding genomic sciences are not effectively utilized in medicine, agriculture and industry. This is partly because of the disconnection between scientists in different disciplines, and because much of the translational research done in both industry and academia is patent-protected and not published in a timely manner. This INCT proposal addre...
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