CV Lattes
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Universidade de São Paulo (USP). Faculdade de Odontologia de Ribeirão Preto (FORP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Dental Surgeon graduated at School of Dentistry of Ribeirão Preto, University of São Paulo (FORP-USP), Brazil (2016-2020). PhD student in Oral Biology and member of research group Bone Research Lab advised by Professor Dr. Márcio Mateus Beloti and Professor Dr. Adalberto Luiz Rosa at Basic and Oral Biology department at FORP - USP with emphasis on Cell Therapy to regenerate bone tissue.E-mail: maria.paula.gomes@usp.br (Source: Lattes Curriculum)
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Cell therapy is one of the strategies of the regenerative medicine with potential for the treatment of large bone defects mainly using Mesenchymal Stem Cells (MSCs) and the study of molecules that act on these cells to favor bone regeneration is essential in this context. Among these molecules, the extracellular matrix protein agrin, which is involved in several biological processes, was …
TBone tissue has high capacity of regeneration, but in several situations the extent of the injury overcomes its regenerative potential. In this scenario, therapies based on the use of mesenchymal stem cells (MSCs) have aroused the attention of many researchers for being a promising alternative compared with the available treatments. However, many molecular, cellular and tissue characteri…
Pyle's disease is a rare skeletal disorder of long bone with wide metaphysis, increased trabecular bone, cortical thinning, and increased fragility fracture risk caused by a genetic deficiency in Secreted Frizzled Receptor Protein 4 (Sfrp4). In Sfrp4 null mice, cortical thinning is due to a deregulation of periosteal bone formation and endosteal remodeling mainly because activation of non…
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