Abstract
Parkinson's disease (PD) is a progressive neurodegenerative disease with devastating clinical manifestations. In PD, neuronal death is associated with intracellular accumulation of aggregated a-synuclein (a-syn), a synaptic protein, forming structures known as Lewy bodies. The disease is found in two main forms: familial PD, comprehending 10% of the cases; and sporadic PD, comprehending 9…