CV Lattes
ORCID
Abstract
Alterations in the FBN1 gene are responsible for causing Marfan Syndrome (MFS), a connective tissue disease characterized for malformation of the microfibrils, which are molecules with an important structural role that act in several functions, including elastin deposition and TGF-² storage. One of MFS's greatest complications is aneurism formation, mainly in the aorta, which can eventual…