graduate at Odontologia from Universidade Estadual Paulista Júlio de Mesquita Filho (1987), master's at Odontology from Universidade Estadual de Campinas (1992) and ph.d. at Odontology from Universidade Estadual de Campinas (1996). Has experience in Odontology, focusing on Odontology, acting on the following subjects: biocompatibilidade, dentina, polpa, cultura de células and citotoxicidade. (Source: Lattes Curriculum)
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The main objectives of the present study is to develop an innovative polymeric primer (PP) containing different concentrations of titanium tetrafluoride (TiF4) catalyst, and to assess its influence on the aesthetic efficacy, morphological changes in dental enamel and cytotoxicity frequently caused by conventional in-office tooth bleaching therapy. For this purpose, standardized enamel/den…
Despite the excellent aesthetic outcome obtained using the in-office dental bleaching therapy, which uses gels with high concentrations of hydrogen peroxide (H2O2), this professional treatment may cause irreversible pulp damage and tooth sensitivity. Thus, new dental bleaching protocols based on the use of gels with low concentrations of H2O2 or shortened periods of gels application on en…
The development of biocompatible and bioactive scaffolds based on biotechnology and tissue engineering concepts is the goal of pulp-dentin complex regeneration. These biomaterials should be able to induce the chemotaxis of resident stem cells to the pulp exposure site, followed by odontoblastic differentiation and deposition of mineralized extracellular matrix. For this specific clinical …
This research project has the challenging purpose of developing innovative tooth bleaching products capable to associate both esthetic and biologic parameters. The optimization of hydroxyl radicals (HO*) generation from hydrogen peroxide (H2O2) at low concentrations will be the principle of these products in order to increase the reactivity with tooth structure. Consequently, the diffusio…
(Only some records are available in English at this moment)
Different concentrations of calcium titanate (CaTiO3) will be added to an at-home bleaching gel with 22% carbamide peroxide (CP22%). The products will be assessed concerning their bleaching effectiveness (BE), trans-enamel dentinal cytotoxicity (TC) and effects on the microstructure of enamel. For this, standardized enamel/dentin discs will be obtained, stained and bleached for 15 days (2…
The main objective of this study is to evaluate the effects of incorporating manganese oxide (MnO2) into a commercial carbamide peroxide (CP) gel on the esthetic efficacy and cytotoxicity of at-home bleaching therapy (HBT). Standardized enamel/dentin discs will be stained and then subjected to HBT for 15 days (2 hours/day), using a 22%CP containing or not MnO2, establishing the following …
The main objective of this study is to develop an innovative polymeric primer (PP) containing different concentrations of the catalyzing agent titanium tetrafluoride (TiF4), which can be used in in-office dental bleaching, aiming to increase the aesthetic efficacy, prevent morphological alterations in the enamel treatment and reduce the cytotoxicity of the therapy. For this, enamel/dentin…
(Only some records are available in English at this moment)
Chemical and enzymatic catalytic agents act directly on the degradation of hydrogen peroxide (H2O2), increasing the aesthetic efficacy and reducing the cytotoxicity caused by the conventional in-office dental bleaching widely employed. Thus, the objective of the present study is to assess the influence of an experimental polymeric catalytic primer (PCP) containing 10 mg/mL of manganese ox…
The photocatalysis as well as the chemical catalysis of hydrogen peroxide (H2O2) present in bleaching gels composition may improve the aesthetic outcome and reduce the cytotoxicity caused by the conventional in-office bleaching therapy. Thus, the objective of the present study is to evaluate the influence of the application on the enamel, of a protective tape (FP) associated with a polyme…
Modifications on implant surface aims to obtain a bioactive substrate capable of improving the interaction between implants and oral tissues specially in challenging and difficult osseointegration conditions. One of the most common surface modification method actually used is the chemical/thermic treatments, which produces a porous bioactive layer on Titanium (Ti) surface allowing the dir…
(Only some records are available in English at this moment)
The main objective of this study is to extract chitosan from the crabs shells to develop a mineral-coated porous chitosan scaffold, which will be assessed using a tri-dimensional (3D) cell culture model concerning its bioactive potential for pulp-dentin complex regeneration. Initially, chitosan will be extracted from crabs shells and then different formulations of porous chitosan scaffold…
The attachment of the oral mucosa to the surface of abutments of dental implants prevents undesired apical migration of the junctional epithelium and reabsorption of the bone crest. The surface modification of implants and their prosthetic components (abutments) can favor cell adhesion improving the aesthetic and functional conditions of the prosthetic rehabilitation. The objective of thi…
Synthetic biomaterials used as bone substitutes should allow an appropriate bone remodeling with a progressive resorption induced by osteoclasts, followed by bone formation and maturation induced by osteoblasts. Previous in vitro studies demonstrated that changes in the surface topography of beta tricalcium phosphate (bTCP) could influence differentiation and survival of osteoclasts and r…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 21 / 16 | Completed research grants |
| 5 / 5 | Ongoing scholarships in Brazil |
| 43 / 32 | Completed scholarships in Brazil |
| 5 / 4 | Completed scholarships abroad |
| 75 / 58 | All research grants and scholarships |
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CV Lattes
ORCID