Abstract
Recent evidence shows that stress-related hormone norepinephrine may influence cancer progression. However, the effects of norepinephrine on cancer onset are poorly known. Chronic tobacco use is the main risk factor for oral cancer development. The carcinogen derived from tobacco 4 (N-methyl-nitrosamino)-1-(3-pyridyl) butan-1-one) (NNK) can induce oral carcinogenesis. There are no studies…