Dr. Fernanda Crunfli received her bachelor's degree in Biomedicine (2011) and a Master's degree in Neurosciences and Behavior by the Biosciences program applied to Health by the Federal University of Alfenas (2013). Ph.D. in Sciences (Human Physiology) from the University of São Paulo (2013-2017) with internship period at Francisco de Vitoria University in Madrid, Spain (2017) in the laboratory of Endocannabinoids and Neuroinflammation headed by Dr. Julián Romero. She was a postdoctoral fellow with the FAEPA scholarship in the Department of Pharmacology at the Medical School of Ribeirão Preto - University of São Paulo (FMRP/USP, 2018-2019). Dr. Fernanda Crunfli, has experience in Neuroscience and Neurophysiology, investigating the cannabinoid system participation in neurodegenerative diseases, specially in Alzheimer's disease, and its underlying intracellular mechanisms. Has experience in techniques used for the development of in vitro and in vivo neurodegeneration models, and evaluation of the therapeutic potential of neuroprotective drugs. It acts in the themes: modulation of the canabinoid system, neurodegenerative diseases, neuronal metabolism and neuroinflammatory processes. (Source: Lattes Curriculum)
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Schizophrenia is considered a multifactorial psychiatric disorder that involves environmental, genetic, and neurodevelopmental dysfunctions. The schizophrenia pathophysiology includes molecular abnormalities in immune, metabolic, and endocrine systems. Despite significant progress in the comprehension of the various manifestations of schizophrenia, the etiology of schizophrenia remains un…
The brain is the most cholesterol-rich organ, accounting for 25% of the total cholesterol present in the human body, and is essential for synaptic transmission. Within the brain, myelin contains the majority of cholesterol, representing 70%, with the other 30% being present in the membranes of neurons and glial cells. Disturbances in cholesterol metabolism and levels are a risk factor for…
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