Abstract
Proteostasis or homeostasis of proteins including synthesis, folding and protein degradation. The chaperone is defined by several chaperones, co-chaperones and enzymes of protein folding and scaffold proteins that regulate one of proteostasis arm. The network hyperconnectivity chaperone know as epichaperome, which hubs are HSP70 and HSP90 is found in a half of teste cancer cells and its d…