Abstract
In skeletal muscle the main monocarboxylic transporters (MCTs) responsible for lactate dynamism are the MCT1 and MCT4 isoforms, associated respectively to influx and eflux of lactate. It is known that physical stress plays a role in modulating the genic expression of MCTs by means of seemingly distinct molecular signaling pathways involving the co-activator peroxisome proliferator activat…