, acting on the following subjects: toxicologia social and química medicinal. (Source: Lattes Curriculum)
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Iron overload is a harmful condition for patients, who have a significant decrease in quality of life. At the same time, iron is a crucial nutrient also for parasites and tumor cells. Iron chelators are high-affinity molecules that present several possibilities for clinical use: (i) metal overload attenuators; (ii) hijackers of essential metals of those same targets; (iii) metalloenzyme i…
Iron overload is a harmful condition for patients, who present a significant decrease in quality of life. Iron chelators are high affinity molecules that present several possibilities for clinical use: (i) metal overload attenuators; (ii) deliverers of toxic metals to selected targets; (iii) hijackers of essential metals of these same targets. Desferrioxamine (DFO), a bacterial siderophor…
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