CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduation at Ciências Biológicas from Pontifícia Universidade Católica de Minas Gerais (2009), master's at Biochemistry from Universidade Federal de Minas Gerais (2011) and doctorate at Biochemistry from Universidade Federal de Minas Gerais (2014). Has experience in Immunology, focusing on Celular Imunology, acting on the following subjects: innate immunty, tlrs, malária, malaria and il-1beta. (Source: Lattes Curriculum)
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The inflammasome is a molecular platform found in the cytoplasm of eukaryotic cells, which activation leads to the processing of caspase-1 and cleavage of IL-1b and IL-18 into their active forms, as well as induction of inflammatory cell death through gasdermin-D activation. The receptor NLRC4, an essential cytosolic sensor for the activation of Naip/NLRC4 inflammasome is triggered by ba…
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