Abstract
This postdoctoral research project aims to describe and to analyze Li-Fraumeni´s Syndrome carriers kinship relations - highlighting the pathogenic variant p.R337H TP53-, which are members of the Li-Fraumeni Syndrome Association of Brazil (LFSA), living in Brazilian Southern and Southeastern Regions. Li-Fraumeni Syndrome, discovered in the late 1960s, is a syndrome that predisposes its car…