José Roberto Fioretto

• Abstract

  Acute respiratory distress syndrome (ARDS) is the most severe form of acute lung injury (ALI). Despite better understanding in the pathophysiology and consequent advancement in therapeutic strategies, mortality rate is still high.The exact mechanism that leads to ARDS is still unknown; however, some evidence suggests that patients with ARDS are exposed to elevated oxidative stress (OS). O…

  Effect of lycopene supplementation in oxidative pulmonary stress in experimental acute lung injury, AP.R

• Abstract

  Oxidative damage has been said to play an important role in pulmonary injury, which is associated with the development and progression of acute respiratory distress syndrome (ARDS). We aimed to identify biomarkers to determine the oxidative stress in an animal model of acute lung injury (ALI) using two different strategies of mechanical ventilation. Rabbits were ventilated using either co…

  Biomarkers for oxidative stress in acute lung injury induced in rabbits submitted to different strategies of mechanical ventilation, PUB.ART

• Abstract

  Mechanical ventilation (MV) is an essential method of support in acute respiratory distress syndrome (ARDS). There are two ventilatory methods of lung protection, protective conventional mechanical ventilation (CMV) and, more recently, high frequency oscillatory ventilation (HFOV). HFOV is a ventilatory method that uses lower tidal volume than the volume of anatomical dead space, often we…

  Prone position associated with high-frequency oscillatory ventilation and conventional protective mechanical ventilation in model of acute respiratory distress syndrome in rabbits, AP.R

(Only some records are available in English at this moment)

• Abstract

  Mechanical ventilation (MV) is an essential method of support in acute respiratory distress syndrome (ARDS). There are two ventilatory methods of lung protection, protective conventional mechanical ventilation (CMV) and, more recently, high frequency oscillatory ventilation (HFOV). HFOV is a ventilatory method that uses lower tidal volume than the volume of anatomical dead space, often we…

  Prone positioning associated with high-frequency oscillatory ventilation and conventional protective mechanical ventilation in an acute respiratory distress syndrome rabbit model., BP.IC

• Abstract

  Background: The acute respiratory distress syndrome (ARDS) is characterized by an inflammatory process that causes a disruption of the alveolar-capillary barrier with consequent interstitial and alveolar edema, decrease in lung compliance, pulmonary hypertension, ventilation/perfusion mismatch, and refractory hypoxemia. Despite its pathophysiology being better understood and recent advanc…

  Effect of different mechanical ventilation techniques on the pulmonary oxidative stress induced by a model of acute respiratory distress syndrome in rabbits, BP.DR