CV Lattes
ORCID
Abstract
Many cytokines with biologically relevant functions in inflammatory diseases such as rheumatoid arthritis and periodontal disease exert their biological functions through the JAK-STAT signal transduction pathway. Activated JAKs phosphorylate the receptor's cytoplasmic domain, inducing the activation of its substrates, mainly proteins known as STATs, which in turn dimerize and translocate …