CV Lattes
ORCID
Abstract
Nonalcoholic fatty liver disease (NAFLD) is a group of diseases characterized by an excess of lipids in the liver, comprising from simple hepatic steatosis (NAFL) to an eventual progression to more serious diseases such as steatohepatitis (NASH) and hepatocellular carcinoma (HCC). The constitutive activation of PI3K-mTORC2-Akt-mTORC1 pathway induced by Pten deletion in hepatocytes promote…