Fabiana Dalla Vecchia Genvigir
CV Lattes
ResearcherID
Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas (FCF) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduate at Farmácia e Bioquímica from Universidade Estadual de Londrina (2005) and master's at Pharmacy from Universidade de São Paulo (2007). Has experience in Pharmacy, acting on the following subjects: prescrição, medicamento, statins, propriedades funcionais and farmácia. (Source: Lattes Curriculum)
- Biotransformation enzymes and transporters: a pharmacogenetic study in renal transplant recipients treated with tacrolimus, everolimus and mycophenolate sodium, BP.PD
Abstract
Understanding the genetic factors involved in variations in responses to immunosuppressants can improve efficacy and limit toxicity in transplant therapy. This pharmacogenetic study aims to investigate associations between genetic polymorphisms that affect the pharmacokinetics of tacrolimus (TAC), everolimus (EVR), and mycophenolate sodium (MPS) and the clinical outcomes in kidney trans...
- Genetic basis of response to immunosuppressive agents, tacrolimus and sirolimus, in renal transplant recipients, BP.PD
Abstract
What makes organ transplantation and the patient response to drug therapy especially complex is the nature of the drugs that are used, the number of polymorphic factors that play a role in drug responsiveness and the lack of understanding of the acute and chronic processes that jeopardize organ function and survival. Today, a major goal of immunosuppressive therapy is the individualized...
- Effect of lipid-lowering drugs on reverse cholesterol transport gene expression, BP.DR
Abstract
ATP-binding cassette transporter A1 (ABCA1) is a transmembrane protein involved on cholesterol and phospholipids cellular efflux, which is an essential step for the cholesterol reverse transport. Polymorphisms in the ABCA1 gene have been associated with increased risk of coronary heart disease, differences on serum lipid profile and response to lowering-cholesterol drugs. Recently we ha...
- Comparative pharmacogenetic study in Brazilian and Spanish kidney transplant recipients treated with tacrolimus and mycophenolate sodium, BE.EP.PD
Abstract
The narrow therapeutic index of the immunosuppressive drugs and the several factors influencing the pharmacological response contribute to make the patient monitoring especially complex in the organ transplantation. That is way, the individualization of treatment is an important tool that can contribute to the reduction of acute rejection events, improve efficacy and decrease the toxic ...
| 3 / 3 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 4 / 4 | All Scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
GENVIGIR‚ F.D.V.; HIRATA‚ M.H.; HIRATA‚ R.D.C.. ABCA1 expression and statins: inhibitory effect in peripheral blood mononuclear cells. PHARMACOGENOMICS, v. 10, n. 6, p. 997-1005, 2009. (07/00398-3)