Abstract
The proteasome is a protein complex of utter importance for cellular homeostasis, as it is one of the main mechanisms of intracellular proteolysis. The proteasome is made up of a catalytic unit called 20S, which can sometimes be coupled to the 19S regulatory unit at one end (forming the 26S proteasome) or at both ends (forming the 30S proteasome). When associated with the 19S regulatory u…