Resumo
Hypercoagulability is a hallmark of sickle cell disease (SCD), and its pathophysiology is related to the concomitant activation of hemostasis and innate immunity, in a process known as immunothrombosis. Among the mechanisms involved in immunothrombosis, the best known are the generation of neutrophil extracellular networks (NETs) and the expression of tissue factor by monocytes, but over …