Abstract
Inflammasomes are multiprotein cytoplasmic complexes capable of activating caspase-1, which in turn cleaves pro-IL-1 beta, pro-IL-18 and Gasdermin-D (GDSMD). GSDMD is able to form pores in the cell membrane resulting in the secretion of active forms of IL-1 beta and IL-18 and induction of cell death by pyroptosis. Several inflammasomes are activated during T. gondii infection, resulting i…